Most online weight loss programs prescribe one of two GLP-1 medications: semaglutide (the active ingredient in Wegovy and Ozempic) or tirzepatide (the active ingredient in Zepbound and Mounjaro). The sticker price depends far less on the molecule than on the format. Brand-name pens bought through telehealth typically run $199 to $499 per month cash-pay, while compounded versions of the same active ingredients start around $89 to $149 per month — with the important caveat that compounded drugs are not FDA-approved, so pharmacy sourcing and testing practices matter enormously.
The advertised price is rarely the price you keep paying. Many providers quote a discounted first month, then step the cost up as your dose titrates upward over four to five months. Others add a separate membership or platform fee on top of the medication itself. A program that looks $60 cheaper at sign-up can cost more by month four — which is why every comparison we publish records the starting price, the price at higher doses, and any required fees side by side.
Before choosing any program, we suggest checking three things: whether a licensed clinician reviews your health history before prescribing, which pharmacy actually fills the prescription, and what it takes to cancel. Those three answers separate the legitimate telehealth platforms from the sites worth avoiding — and they are exactly what our reviews document for every brand we cover.